CPHON Exam Study Guide 2026-2027 | Pediatric Hematology Oncology Nurse Certification Prep | 200 Practice Questions

A complete study guide for the CPHON® exam, the ONCC certification for pediatric hematology/oncology nurses. Organized around the six subject areas of the official CPHON Test Content Outline, with exam-level practice questions written as clinical scenarios.

What's Inside:

• Exam overview: 165 questions (125 scored), 3 hours, the official subject-area weights, scaled scoring (55 to pass), eligibility, fees and renewal
• Content review in 6 sections and 31 topics: transitions of care, immunizations, survivorship and late effects, end-of-life care; cancer biology and genetics, childhood cancers, blood disorders, diagnostics and staging, clinical trials, ethics and professional practice; chemotherapy, biotherapy and targeted therapy, CAR T-cells, radiation and surgery, stem cell transplant, blood products and coagulation therapy; pain, fatigue, nutrition, system-specific effects, devices and infection prevention; every emergency on the outline from sepsis and tumor lysis to SIADH, spinal cord compression, anaphylaxis and extravasation; development, family, culture, gender identity, community resources and grief
• 2 practice tests with 200 exam-level questions weighted like the real test, mostly priority and clinical-judgment scenarios with dosage calculations
• Detailed answer explanations for every question, including why the tempting wrong answers are wrong
• Quick-reference tables and flows: CRS and ICANS grading, transfusion reactions, blood product modifications, extravasation antidotes, SIADH vs DI vs cerebral salt wasting, cytogenetic risk markers, predisposition syndromes, levels of care, and more

Format:

• Digital PDF, instant download
• 161 printable US Letter pages

This is an independent study resource and is not affiliated with or endorsed by the Oncology Nursing Certification Corporation (ONCC). CPHON® is a registered trademark of ONCC.