Informatics Nurse NI-BC Study Guide 2026–2027 | 200 Practice Questions

Prepare for the ANCC Informatics Nursing Board Certification exam with a study guide built on the current ANCC test content outline. Every section follows the outline's three domains and twelve subdomains, so your study time maps directly to how the exam is weighted.

This 97-page digital guide pairs a focused content review with two 100-question practice tests of scenario-based, exam-level questions, so you practice the judgment the exam rewards: the informatics nurse's first action, the best standard for a data-exchange problem, and the right response at each phase of the system design lifecycle.

What's Inside

• An overview of the current exam: 150 items (125 scored, 25 pretest) in 3 hours, the domain weighting (36% / 35% / 29%), eligibility, fees, scoring, and retesting
• Foundations of Practice: the ANA definition and scope and standards, roles and competencies, management fundamentals, evidence-based practice and health equity, DIKW and informatics theories, systems theory, Lewin, Kotter, Rogers, ADKAR, PDSA, Lean, Six Sigma, RCA and FMEA, HIPAA Privacy, Security, and Breach Notification Rules, de-identification, HITECH and Promoting Interoperability, Cures Act information blocking, CMS and Joint Commission requirements, ethics and AI ethics, communication, team building, and conflict management
• System Design Lifecycle: project management (charter, WBS, critical path, earned value), requirements gathering, workflow and swim lane diagrams, feasibility, vendor selection, strategic planning, SWOT, enterprise architecture, interoperability levels, clinical content build, the CDS Five Rights and alert fatigue, usability heuristics, testing types, ADDIE training, go-live strategies, support tiers, change control, downtime and back-loading, and evaluation with SUS and KPIs
• Data Management and Healthcare Technology: the ANA-recognized nursing terminologies, SNOMED CT, LOINC, RxNorm, ICD-10, HL7 v2 messages, FHIR, C-CDA, USCDI, database design and keys, ETL and data warehouses, MPI errors, data migration, SQL queries with worked results, sensitivity, specificity and PPV, control charts, AI models, BCMA, smart pumps, device integration, telehealth, cloud models, and cybersecurity
• Schematic diagrams (DIKW pyramid, system design lifecycle, swim lane workflow, entity-relationship), 45+ quick-reference tables, flowcharts, and charts
• A Final Review Checklist with a high-yield formula table, 12-, 6-, and 4-week study schedules, FAQs, test-taking strategies, and recommended resources
• 2 practice tests (200 questions) with a quick answer grid and a detailed explanation for every answer

Format

• Instant digital download (PDF), 8.5 × 11 in
• Clickable table of contents
• Print it or study on a tablet, laptop, or phone

Please note: This is a digital product. No physical item will be shipped.

NI-BC™ is a trademark of the American Nurses Credentialing Center (ANCC). Test Treasure Publication is not affiliated with or endorsed by ANCC or any testing organization; all exam and organization names referenced are trademarks of their respective owners.