PANRE Study Guide 2027–2028 | Physician Assistant Recertification Exam Prep incl. Longitudinal Assessment, 200 Questions (PDF)

Prepare for PA recertification with a complete study guide for the Physician Assistant National Recertifying Examination (PANRE) and the PANRE Longitudinal Assessment (PANRE-LA), organized by the 15 categories of the official NCCPA Content Blueprint for PANRE and PANRE-LA. Every section reviews the core generalist medicine the exam tests: the most likely diagnosis, the best initial and most accurate test, the next step and current first-line therapy.

What's Inside

• Exam overview for both routes: the 10-year cycle, PANRE versus PANRE-LA, the content blueprint and task areas, question format, scoring, fees and attempts

• Cardiovascular, Pulmonary, and Gastrointestinal/Nutrition: hypertension and lipids, ACS, heart failure, arrhythmias, valve disease, asthma and COPD, pneumonia, PE, ABGs, liver, biliary and GI bleeding

• Endocrine, Eyes, Ears, Nose and Throat, Musculoskeletal, Infectious Diseases and Psychiatry/Behavioral Science

• Neurologic, Dermatologic, Renal, Genitourinary, Reproductive and Hematologic systems, plus Emergent Topics (legal, ethical and DEI)

• Diagrams and flowcharts for HFrEF therapy, STEMI reperfusion, DKA, sepsis, acute stroke and hyperkalemia, plus 269 quick-reference tables

• Worked examples for clinical calculations (anion gap, Winter formula, FENa, CHA2DS2-VASc, Parkland, corrected sodium and more)

• Exam Tips, Common Traps, Memory Aids and Clinical Scenarios in every chapter

• 4-, 8- and 12-week study plans for the proctored PANRE and a quarter-by-quarter plan for PANRE-LA, with FAQs and test-taking strategies

• 2 practice tests of 100 questions each (200 questions total), five answer options per question, weighted like the official blueprint, with a complete answer key and an explanation for every question

Format

• Instant digital download (PDF), 8.5 × 11 in

• Clickable table of contents

• Print it or study on a tablet, laptop or phone

Please note: This is a digital product. No physical item will be shipped.

This is an independent study resource and is not affiliated with or endorsed by the National Commission on Certification of Physician Assistants (NCCPA).